mRNA stability and selenocysteine insertion sequence efficiency rank gastrointestinal glutathione peroxidase high in the hierarchy of selenoproteins.

@article{Wingler1999mRNASA,
  title={mRNA stability and selenocysteine insertion sequence efficiency rank gastrointestinal glutathione peroxidase high in the hierarchy of selenoproteins.},
  author={Kirstin Wingler and M. B{\"o}cher and Leopold Floh{\'e} and Heike Kollmus and Regina Brigelius-Floh{\'e}},
  journal={European journal of biochemistry},
  year={1999},
  volume={259 1-2},
  pages={149-57}
}
The recently described gastrointestinal glutathione peroxidase (GI-GPx) is the fourth member of the family of the selenoenzymes glutathione peroxidases (GPx). In contrast to the more uniform distribution of, for example, the classical glutathione peroxidase (cGPx), it is expressed exclusively in the gastrointestinal tract and has, therefore, been suggested to function as a primary barrier against alimentary hydroperoxides. In order to get an idea of its relative importance we investigated its… CONTINUE READING