mRNA expression and release of interleukin-8 induced by serum amyloid A in neutrophils and monocytes.

@article{Ribeiro2003mRNAEA,
  title={mRNA expression and release of interleukin-8 induced by serum amyloid A in neutrophils and monocytes.},
  author={Fernanda Pereira Ribeiro and Cristiane Jaciara Furlaneto and Elaine Hatanaka and Wesley Bueno Ribeiro and Gl{\'a}ucia Mendes Souza and Marco A Cassatella and Ana M. Sanchez de la Campa},
  journal={Mediators of Inflammation},
  year={2003},
  volume={12},
  pages={173 - 178}
}
The acute phase response is a systemic reaction to inflammatory processes characterized by multiple physiological adaptations, including the hepatic synthesis of acute-phase proteins. In humans, serum amyloid A (SAA) is one of the most prominent of these proteins. Despite the huge increase of serum levels of SAA in inflammation, its biological role remains to be elucidated, even though SAA is undoubtedly active in neutrophils. In a previous study, we reported that SAA induces the release of… CONTINUE READING

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The release of IL-8 from SAA - stimulated neutrophils is strongly suppressed by the addition of N - acetyl - l - cysteine , alpha - mercaptoethanol , glutathione , and dexamethasone .
The release of IL-8 from SAA - stimulated neutrophils is strongly suppressed by the addition of N - acetyl - l - cysteine , alpha - mercaptoethanol , glutathione , and dexamethasone .
In a previous study , we reported that SAA induces the release of tumor necrosis factor - alpha , interleukin ( IL)-1beta and IL-8 from human blood neutrophils .
In a previous study , we reported that SAA induces the release of tumor necrosis factor - alpha , interleukin ( IL)-1beta and IL-8 from human blood neutrophils .
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