mRNA expression and phenotype of odontogenic tumours in the v-Ha-ras transgenic mouse.

@article{Dodds2003mRNAEA,
  title={mRNA expression and phenotype of odontogenic tumours in the v-Ha-ras transgenic mouse.},
  author={Anne Dodds and Ronald E. Cannon and Christie L. Suggs and John Timothy Wright},
  journal={Archives of oral biology},
  year={2003},
  volume={48 12},
  pages={
          843-50
        }
}
UNLABELLED Ameloblastomas are the most common odontogenic neoplasia in humans, and although typically considered locally invasive and benign, frequently recur subsequent to surgical resection. The Tg.AC transgenic mouse carrying the v-Ha-ras oncogene has been found to spontaneously develop ameloblastoma-like tumours (35% by 1 year of age) that are rare in the wild type FVB background strain. OBJECTIVE The purpose of this study was to characterise the mRNA expression of genes in the mouse… CONTINUE READING
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