mRNA and microRNA expression profiles of the NCI-60 integrated with drug activities.

@article{Liu2010mRNAAM,
  title={mRNA and microRNA expression profiles of the NCI-60 integrated with drug activities.},
  author={Hongfang Liu and Petula N D'Andrade and Stephanie Fulmer-Smentek and Philip Lorenzi and Kurt W. Kohn and John N. Weinstein and Yves Pommier and William C. Reinhold},
  journal={Molecular cancer therapeutics},
  year={2010},
  volume={9 5},
  pages={1080-91}
}
As part of the Spotlight on Molecular Profiling series, we present here new profiling studies of mRNA and microRNA expression for the 60 cell lines of the National Cancer Institute (NCI) Developmental Therapeutics program (DTP) drug screen (NCI-60) using the 41,000-probe Agilent Whole Human Genome Oligo Microarray and the 15,000-feature Agilent Human microRNA Microarray V2. The expression levels of approximately 21,000 genes and 723 human microRNAs were measured. These profiling studies include… CONTINUE READING