mRNA and micro-RNA expression analysis in laser-capture microdissected prostate biopsies: valuable tool for risk assessment and prevention trials.

@article{Nonn2010mRNAAM,
  title={mRNA and micro-RNA expression analysis in laser-capture microdissected prostate biopsies: valuable tool for risk assessment and prevention trials.},
  author={Larisa Nonn and Avani Vaishnav and Lindsay Gallagher and Peter H. Gann},
  journal={Experimental and molecular pathology},
  year={2010},
  volume={88 1},
  pages={45-51}
}
Diagnosis of prostate cancer (PCa) typically relies on needle biopsies, which are routinely archived in paraffin after formalin fixation and may contain valuable risk or prognostic information. The objective of this study was to determine the feasibility of mRNA and miRNA expression analysis in laser-capture microdissected (LCM) formalin-fixed paraffin-embedded archived prostate biopsies compared to the gold standard of frozen tissue. We analyzed the expression of compartment-specific and PCa… CONTINUE READING

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