mRNA Localization: Gene Expression in the Spatial Dimension

@article{Martin2009mRNALG,
  title={mRNA Localization: Gene Expression in the Spatial Dimension},
  author={Kelsey C Martin and Anne Ephrussi},
  journal={Cell},
  year={2009},
  volume={136},
  pages={719-730}
}
The localization of mRNAs to subcellular compartments provides a mechanism for regulating gene expression with exquisite temporal and spatial control. Recent studies suggest that a large fraction of mRNAs localize to distinct cytoplasmic domains. In this Review, we focus on cis-acting RNA localization elements, RNA-binding proteins, and the assembly of… CONTINUE READING