mGluR7 Is a Metaplastic Switch Controlling Bidirectional Plasticity of Feedforward Inhibition

@article{Pelkey2005mGluR7IA,
  title={mGluR7 Is a Metaplastic Switch Controlling Bidirectional Plasticity of Feedforward Inhibition},
  author={Kenneth A. Pelkey and Gabriela Lavezzari and Claudia Racca and Katherine W. Roche and Chris J McBain},
  journal={Neuron},
  year={2005},
  volume={46},
  pages={89-102}
}
Plasticity of feedforward inhibition in the hippocampal mossy fiber (MF) pathway can dramatically influence dentate gyrus-CA3 dialog. Interestingly, MF inputs to CA3 stratum lucidum interneurons (SLINs) undergo long-term depression (LTD) following high-frequency stimulation (HFS), in contrast to MF-pyramid (PYR) synapses, where long-term potentiation (LTP) occurs. Furthermore, activity-induced potentiation of MF-SLIN transmission has not previously been observed. Here we report that… CONTINUE READING
Highly Influential
This paper has highly influenced 17 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 82 extracted citations

Presynaptic long-term plasticity

Front. Synaptic Neurosci. • 2013
View 4 Excerpts
Highly Influenced

Associative plasticity at excitatory synapses facilitates recruitment of fast-spiking interneurons in the dentate gyrus.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2010
View 18 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 52 references

Differential presynaptic localization of metabotropic glutamate receptor subtypes in the rat hippocampus.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 1997
View 20 Excerpts
Highly Influenced

Selective blockade of P/Q-type calcium channels by the metabotropic glutamate receptor type 7 involves a phospholipase C pathway in neurons.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2000
View 3 Excerpts
Highly Influenced

A frequencydependent switch from inhibiton to excitation in a hippocampal unitary circuit

M. Mori, M. H. Abegg, B. H. Gawhiler, U. Gerber
Nature • 2004
View 1 Excerpt

Subunit-specific regulation of NMDA receptor endocytosis.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2004
View 1 Excerpt

Two Loci of expression for long-term depression at hippocampal mossy fiber-interneuron synapses.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2004
View 8 Excerpts

A large pool of releasable vesicles in a cortical glutamatergic synapse.

Proceedings of the National Academy of Sciences of the United States of America • 2003
View 1 Excerpt

Similar Papers

Loading similar papers…