m-Calpain colocalizes with the calcium-sensing receptor (CaR) in caveolae in parathyroid cells and participates in degradation of the CaR.

Abstract

The calcium-sensing receptor (CaR) is a G protein-coupled, seven-transmembrane receptor and resides within caveolin-rich membrane domains in bovine parathyroid cells. The proenzyme of calpain 2 (m-calpain) is a heterodimeric calcium-dependent cysteine protease consisting of catalytic and regulatory subunits. The effects of calcium on the enzyme include… (More)

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Cite this paper

@article{Kifor2003mCalpainCW, title={m-Calpain colocalizes with the calcium-sensing receptor (CaR) in caveolae in parathyroid cells and participates in degradation of the CaR.}, author={Olga Kifor and Imre Kifor and Francis D. Moore and Robert R Butters and Edward Brown}, journal={The Journal of biological chemistry}, year={2003}, volume={278 33}, pages={31167-76} }