lodGWAS: a software package for genome-wide association analysis of biomarkers with a limit of detection

Abstract

UNLABELLED Genome-wide association study (GWAS) of a biomarker is complicated when the assay procedure of the biomarker is restricted by a Limit of Detection (LOD). Those observations falling outside the LOD cannot be simply discarded, but should be included into the analysis by applying an appropriate statistical method. However, the problem of LOD in GWAS… (More)
DOI: 10.1093/bioinformatics/btw021

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Cite this paper

@article{Vaez2016lodGWASAS, title={lodGWAS: a software package for genome-wide association analysis of biomarkers with a limit of detection}, author={Ahmad Vaez and Peter J. van der Most and Bram P. Prins and Harold Snieder and Edwin R. van den Heuvel and Behrooz Z. Alizadeh and Ilja M. Nolte}, journal={Bioinformatics}, year={2016}, volume={32 10}, pages={1552-4} }