lncRNAs: novel players in intervertebral disc degeneration and osteoarthritis.

  title={lncRNAs: novel players in intervertebral disc degeneration and osteoarthritis.},
  author={W Chen and Xiao-hua Yu and Wei Yang and Cheng Wang and W He and Yi-guo Yan and Jian Zhang and Wenjun Wang},
  journal={Cell proliferation},
  volume={50 1}
The term long non-coding RNA (lncRNA) refers to a group of RNAs with length more than 200 nucleotides, limited protein-coding potential, and having widespread biological functions, including regulation of transcriptional patterns and protein activity, formation of endogenous small interfering RNAs (siRNAs) and natural microRNA (miRNA) sponges. Intervertebral disc degeneration (IDD) and osteoarthritis (OA) are the most common chronic, prevalent and age-related degenerative musculoskeletal… CONTINUE READING


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