lncRNA-Map2k4 sequesters miR-199a to promote FGF1 expression and spinal cord neuron growth.

@article{Lv2017lncRNAMap2k4SM,
  title={lncRNA-Map2k4 sequesters miR-199a to promote FGF1 expression and spinal cord neuron growth.},
  author={Hao-Ran Lv},
  journal={Biochemical and biophysical research communications},
  year={2017},
  volume={490 3},
  pages={948-954}
}
Spinal cord injury (SCI) is a common critical illness in clinical practice. SCI prevention, treatment and rehabilitation have become important topics in today's medical profession. Studies have shown that long noncoding RNAs (lncRNAs) also play an important role in the pathology of SCI. The biology software analysis identified miR-199a binding sites in the lncRNA-Map2k4 and FGF1 sequences, which were confirmed by the subsequent dual luciferase reporter assay. When lncRNA-Map2k4 expression was… CONTINUE READING