limma powers differential expression analyses for RNA-sequencing and microarray studies

  title={limma powers differential expression analyses for RNA-sequencing and microarray studies},
  author={Matthew E. Ritchie and Belinda Phipson and D Ying Wu and Yifang Hu and Charity W. Law and Wei Shi and Gordon K Smyth},
  booktitle={Nucleic acids research},
limma is an R/Bioconductor software package that provides an integrated solution for analysing data from gene expression experiments. It contains rich features for handling complex experimental designs and for information borrowing to overcome the problem of small sample sizes. Over the past decade, limma has been a popular choice for gene discovery through differential expression analyses of microarray and high-throughput PCR data. The package contains particularly strong facilities for… CONTINUE READING
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