• Corpus ID: 214775008

lambda DNA through a plasmonic nanopore What can be detected by means of Surface Enhanced Raman Scattering?

  title={lambda DNA through a plasmonic nanopore What can be detected by means of Surface Enhanced Raman Scattering?},
  author={Aliaksandr Hubarevich and Jian‐An Huang and Giorgia Giovannini and Andrea Schirato and Yingqi Zhao and N. Maccaferri and Francesco de Angelis and Alessandro Alabastri and Denis Garoli},
Engineered electromagnetic fields in plasmonic nanopores enable enhanced optical detection and their use in single molecule sequencing. Here, a plasmonic nanopore prepared in a thick nanoporous film is used to investigate the interaction between the metal and a long-chain double strand DNA molecule. We discuss how the matrix of nanoporous metal can interact with the molecule thanks to: i) transient aspecific interactions between the porous surface and DNA and ii) optical forces exerted by the… 
2 Citations

Figures from this paper

Analytical Model for Particle Capture in Nanopores Elucidates Competition among Electrophoresis, Electroosmosis, and Dielectrophoresis
A theory for particle capture in nanopores was developed and derived analytical expressions for the capture rate under the concurrent action of electrical forces, fluid advection, and Brownian motion and it is predicted that dielectrophoresis is able to induce capture for both positive and negative voltages.
A counter-intuitive method for slowing down an analyte in a nanopore and its application to polymer sequencing and analysis
A counter-intuitive method based on reversing the pore voltage and/or increasing analyte mobility by changing the solution pH is described, which can be used for free nucleotides, single amino acids, oligonucleotides/DNA strands, and oligopeptides/proteins.