l-Theanine elicits umami taste via the T1R1 + T1R3 umami taste receptor

  title={l-Theanine elicits umami taste via the T1R1 + T1R3 umami taste receptor},
  author={Masataka Narukawa and Y. Toda and Tomoya Nakagita and Y. Hayashi and T. Misaka},
  journal={Amino Acids},
  • Masataka Narukawa, Y. Toda, +2 authors T. Misaka
  • Published 2014
  • Chemistry, Medicine
  • Amino Acids
  • Abstractl-Theanine is a unique amino acid present in green tea. It elicits umami taste and has a considerable effect on tea taste and quality. We investigated l-theanine activity on the T1R1 + T1R3 umami taste receptor. l-Theanine activated T1R1 + T1R3-expressing cells and showed a synergistic response with inosine 5′-monophosphate. The site-directed mutagenesis analysis revealed that l-theanine binds to l-amino acid binding site in the Venus flytrap domain of T1R1. This study shows that l… CONTINUE READING
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