l-Malate (−2) Protonation State is Required for Efficient Decarboxylation to l-Lactate by the Malolactic Enzyme of Oenococcus oeni

@article{Acevedo2020lMalateP,
  title={l-Malate (−2) Protonation State is Required for Efficient Decarboxylation to l-Lactate by the Malolactic Enzyme of Oenococcus oeni},
  author={Waldo Acevedo and Pablo M. Ca{\~n}{\'o}n and Felipe G{\'o}mez-Alvear and Jaime Huerta and Daniel Aguayo and Eduardo Agosin},
  journal={Molecules},
  year={2020},
  volume={25}
}
Malolactic fermentation (MLF) is responsible for the decarboxylation of l-malic into lactic acid in most red wines and some white wines. It reduces the acidity of wine, improves flavor complexity and microbiological stability. Despite its industrial interest, the MLF mechanism is not fully understood. The objective of this study was to provide new insights into the role of pH on the binding of malic acid to the malolactic enzyme (MLE) of Oenococcus oeni. To this end, sequence similarity… Expand
1 Citations
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