l-DOPA and psychosis: Evidence for l-DOPA-induced increases in prefrontal cortex dopamine and in serum corticosterone

@article{Carey1995lDOPA,
  title={
 l-DOPA and psychosis: Evidence for l-DOPA-induced increases in prefrontal cortex dopamine and in serum corticosterone},
  author={Robert J. Carey and Marinete Pinheiro-Carrera and Huiliang Dai and Carlos Alberto Bezerra Tomaz and Joseph P. Huston},
  journal={Biological Psychiatry},
  year={1995},
  volume={38},
  pages={669-676}
}
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Elevated dopamine in the medial prefrontal cortex suppresses cocaine seeking via D1 receptor overstimulation
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Results suggest that stimulation of D1 receptors in the dorsal mPFC plays a crucial role in cocaine‐induced reinstatement of cocaine seeking, whereas the suppressant effect of DBH inhibitors and L‐DOPA on drug‐ induced reinstatement is mediated by a supra‐maximal stimulation ofD1 receptors leading to their inactivation.
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