l(3)malignant brain tumor and three novel genes are required for Drosophila germ-cell formation.

@article{Yohn2003l3malignantBT,
  title={l(3)malignant brain tumor and three novel genes are required for Drosophila germ-cell formation.},
  author={Christopher B. Yohn and Leslie Pusateri and V{\'i}tor Barbosa and Ruth Lehmann},
  journal={Genetics},
  year={2003},
  volume={165 4},
  pages={1889-900}
}
To identify genes involved in the process of germ-cell formation in Drosophila, a maternal-effect screen using the FLP/FRT-ovoD method was performed on chromosome 3R. In addition to expected mutations in the germ-cell determinant oskar and in other genes known to be involved in the process, several novel mutations caused defects in germ-cell formation. Mutations in any of three genes [l(3)malignant brain tumor, shackleton, and out of sync] affect the synchronous mitotic divisions and nuclear… CONTINUE READING

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