induces apoptosis in human metastatic breast cancer cells by altering intracellular Ca 2 + and the ratio of Bax and Bcl - 2

Abstract

We have recently demonstrated that non-metastatic human breast cancer cell lines undergo apoptosis following phagocytosis of S. cerevisiae. In this study, we investigated the apoptotic effect of heat-killed yeast against human metastatic breast cancer (MBC) cells, MDA-MB-231 in vitro, and the underlying mechanistic bases of this effect. Results show that… (More)

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