induced Growth Inhibition 325-Hydroxyvitamin D Cells Correlates with Decreased Susceptibility to-hydroxylase Activity in Human Prostate Cancer α Reduced 1 Updated

@inproceedings{Hsu2001inducedGI,
  title={induced Growth Inhibition 325-Hydroxyvitamin D Cells Correlates with Decreased Susceptibility to-hydroxylase Activity in Human Prostate Cancer α Reduced 1 Updated},
  author={J Hsu and David Feldman and John E. McNeal and Donna M. Peehl},
  year={2001}
}
Evidence from epidemiological, molecular, and genetic studies suggests a role for vitamin D in the development and/or progression of prostate cancer. In experimental models and clinical trials, 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] was shown to exert antiproliferative, prodifferentiating, and antimetastatic/invasive effects on prostatic epithelial cells. Because the direct clinical application of 1,25(OH)2D3 is limited by the major side effect of hypercalcemia, we investigated the potential… CONTINUE READING
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