in Vitro Effect of Deoxynivalenol on the Differentiation of Human Colonic Cell Lines Caco-2 and t84

@article{Kasuga2004inVE,
  title={in Vitro Effect of Deoxynivalenol on the Differentiation of Human Colonic Cell Lines Caco-2 and t84},
  author={F. Kasuga and Y. Hara-Kudo and N. Saito and S. Kumagai and Y. Sugita‐Konishi},
  journal={Mycopathologia},
  year={2004},
  volume={142},
  pages={161-167}
}
The effects of low concentrations of deoxynivalenol (DON) on structural and functional characteristics of human colonic adenocarcinoma cell lines Caco-2 and T84 were examined. Scanning electron microscopic (SEM) analysis of the apical surfaces of Caco-2 cells revealed reduction or abnormal formation of brush borders in the presence of 50, 100 and 200 ng/ml of DON. Monolayer integrity of Caco-2 and T84 cells was studied using cells which were cultured on permeable membranes. The transepithelial… Expand
Physio-pathological parameters affect the activation of inflammatory pathways by deoxynivalenol in Caco-2 cells.
Toxicity of deoxynivalenol and its acetylated derivatives on the intestine: differential effects on morphology, barrier function, tight junction proteins, and mitogen-activated protein kinases.
The mycotoxin patulin increases colonic epithelial permeability in vitro.
  • H. Mohan, D. Collins, +5 authors A. Baird
  • Chemistry, Medicine
  • Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
  • 2012
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 34 REFERENCES
Epithelial properties of human intestinal Caco-2 cells cultured in a serum-free medium
Immunosuppressive properties of deoxynivalenol.
Effect of cell polarization and differentiation on entry of Listeria monocytogenes into the enterocyte-like Caco-2 cell line.
Sensitivity of cultured human and mouse fibroblasts to trichothecenes.
How intestinal epithelial cell differentiation inhibits the cell-entry of Yersinia pseudotuberculosis in colon carcinoma Caco-2 cell line in culture.
Influence of subchronic exposure to low dietary deoxynivalenol, a trichothecene mycotoxin, on intestinal absorption of nutrients in mice.
...
1
2
3
4
...