implication of the structure of the Helicobacter pylori cag pathogenicity island in induction of interleukin-8 secretion.

@article{Audibert2001implicationOT,
  title={implication of the structure of the Helicobacter pylori cag pathogenicity island in induction of interleukin-8 secretion.},
  author={Calgary AB François Audibert and Christophe Burucoa and Blandine Janvier and J. L. Fauch{\`e}re},
  journal={Infection and immunity},
  year={2001},
  volume={69 3},
  pages={1625-9}
}
Helicobacter pylori virulence is associated with the presence of the cag pathogenicity island (PAI). The cag PAI is involved in the ability to induce interleukin-8 (IL-8) secretion by human cells, which is implicated in the inflammatory response of the gastric mucosa to H. pylori infection. The aim of this study was to determine whether the genetic structure of the cag PAI is conserved and whether it is linked to IL-8 induction ability. Detection of specific markers (cagA, picB, cag13-cag14… CONTINUE READING

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