iTRAQ-based quantitative proteomics reveals important host factors involved in the high pathogenicity of the H5N1 avian influenza virus in mice

Abstract

We previously reported a pair of H5N1 avian influenza viruses which are genetically similar but differ greatly in their virulence in mice. A/Chicken/Jiangsu/k0402/2010 (CK10) is highly lethal to mice, whereas A/Goose/Jiangsu/k0403/2010 (GS10) is avirulent. In this study, to investigate the host factors that account for their virulence discrepancy, we… (More)
DOI: 10.1007/s00430-016-0489-3

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Cite this paper

@article{Hu2016iTRAQbasedQP, title={iTRAQ-based quantitative proteomics reveals important host factors involved in the high pathogenicity of the H5N1 avian influenza virus in mice}, author={Jiao Hu and Zhao Ya Gao and Xiaoquan Wang and Min Gu and Yanyan Liang and Xiaowen Liu and Shunling Hu and Huimou Liu and Wenbo Liu and Sujuan Chen and Daxin Peng and Xiufan Liu}, journal={Medical Microbiology and Immunology}, year={2016}, volume={206}, pages={125-147} }