iPS cells produce viable mice through tetraploid complementation

@article{Zhao2009iPSCP,
  title={iPS cells produce viable mice through tetraploid complementation},
  author={Xiao-Yang Zhao and Wei Li and Zhuo Lv and Lei Liu and Man Tong and T. Hai and J. Hao and Chang-long Guo and Q. Ma and Liu Wang and F. Zeng and Qi Zhou},
  journal={Nature},
  year={2009},
  volume={461},
  pages={86-90}
}
Since the initial description of induced pluripotent stem (iPS) cells created by forced expression of four transcription factors in mouse fibroblasts, the technique has been used to generate embryonic stem (ES)-cell-like pluripotent cells from a variety of cell types in other species, including primates and rat. It has become a popular means to reprogram somatic genomes into an embryonic-like pluripotent state, and a preferred alternative to somatic-cell nuclear transfer and somatic-cell fusion… Expand
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