iNOS expression by activated neutrophils from patients with sepsis.

@article{Tsukahara2001iNOSEB,
  title={iNOS expression by activated neutrophils from patients with sepsis.},
  author={Yasuhiro Tsukahara and Takashi Morisaki and Mizu Kojima and Aya Uchiyama and Makoto Tanaka},
  journal={ANZ journal of surgery},
  year={2001},
  volume={71 1},
  pages={15-20}
}
BACKGROUND Enhanced production of nitric oxide (NO) is associated with various inflammatory diseases such as sepsis. Although activated neutrophils are presumably involved in septic organ injury, the expression of inducible nitric oxide synthase (iNOS) by these cells has not been elucidated. The authors investigated whether activated neutrophils in sepsis could induce mRNA for iNOS and produce NO. METHODS Peripheral blood neutrophils were obtained from healthy volunteers, and septic patients… CONTINUE READING