iMapper: a web application for the automated analysis and mapping of insertional mutagenesis sequence data against Ensembl genomes

@inproceedings{Kong2008iMapperAW,
  title={iMapper: a web application for the automated analysis and mapping of insertional mutagenesis sequence data against Ensembl genomes},
  author={Jun Kong and Fei Zhu and Jim Stalker and David J. Adams},
  booktitle={Bioinformatics},
  year={2008}
}
SUMMARY Insertional mutagenesis is a powerful method for gene discovery. To identify the location of insertion sites in the genome linker based polymerase chain reaction (PCR) methods (such as splinkerette-PCR) may be employed. We have developed a web application called iMapper (Insertional Mutagenesis Mapping and Analysis Tool) for the efficient analysis of insertion site sequence reads against vertebrate and invertebrate Ensembl genomes. Taking linker based sequences as input, iMapper scans… CONTINUE READING

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