iHyd-PseAAC: Predicting Hydroxyproline and Hydroxylysine in Proteins by Incorporating Dipeptide Position-Specific Propensity into Pseudo Amino Acid Composition

@inproceedings{Xu2014iHydPseAACPH,
  title={iHyd-PseAAC: Predicting Hydroxyproline and Hydroxylysine in Proteins by Incorporating Dipeptide Position-Specific Propensity into Pseudo Amino Acid Composition},
  author={Yan Xu and Xin Wen and X. Shao and Nai-Yang Deng and Kuo-Chen Chou},
  booktitle={International journal of molecular sciences},
  year={2014}
}
Post-translational modifications (PTMs) play crucial roles in various cell functions and biological processes. Protein hydroxylation is one type of PTM that usually occurs at the sites of proline and lysine. Given an uncharacterized protein sequence, which site of its Pro (or Lys) can be hydroxylated and which site cannot? This is a challenging problem, not only for in-depth understanding of the hydroxylation mechanism, but also for drug development, because protein hydroxylation is closely… CONTINUE READING

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References

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Showing 1-10 of 63 references

Review: Prediction of protein signal sequences

  • K. C. Chou
  • Curr. Protein Peptide Sci. 2002,
  • 2014
Highly Influential
7 Excerpts

Prediction of protein signal sequences and their cleavage sites

  • K. C. Chou
  • Proteins: Struct. Funct. Genet
  • 2001
Highly Influential
6 Excerpts

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