iASPPsv antagonizes apoptosis induced by chemotherapeutic agents in MCF-7 cells and mouse thymocytes.

Abstract

iASPP was an inhibitory member of ASPP family and could specifically inhibit the apoptotic function of p53. iASPPsv was identified by our lab as the short isoform of iASPP, which encoded a 407 aa protein and highly matched the carboxyl terminus of iASPP. In this study, iASPPsv was stably transfected into the breast cancer cell line MCF-7 by means of… (More)
DOI: 10.1016/j.bbrc.2012.06.124

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@article{Wang2012iASPPsvAA, title={iASPPsv antagonizes apoptosis induced by chemotherapeutic agents in MCF-7 cells and mouse thymocytes.}, author={Lin Wang and Haiyan Xing and Zheng Tian and Leiwen Peng and Yan Li and Kejing Tang and Qing Rao and Min Wang and Jianxiang Wang}, journal={Biochemical and biophysical research communications}, year={2012}, volume={424 3}, pages={414-20} }