huASH1 protein, a putative transcription factor encoded by a human homologue of the Drosophila ash1 gene, localizes to both nuclei and cell-cell tight junctions.

@article{Nakamura2000huASH1PA,
  title={huASH1 protein, a putative transcription factor encoded by a human homologue of the Drosophila ash1 gene, localizes to both nuclei and cell-cell tight junctions.},
  author={Tatsuya Nakamura and Janna Blechman and Shinichiro Tada and Tatiana Rozovskaia and Takahiro Itoyama and Florencia Bullrich and A. Baroja Mazo and Carlo M. Croce and Benjamin Geiger and Eli Canaani},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2000},
  volume={97 13},
  pages={7284-9}
}
During animal development, regions of the embryo become committed to position-specific identities, which are determined by spatially restricted expression of Hox/homeotic genes. This expression pattern is initially established by the activity of the segmentation genes and is subsequently maintained during the proliferative stage through the action of transcription factors encoded by the trithorax (trx) and Polycomb (Pc) groups of genes. trithorax (trx)and ash1 (absent, small, or homeotic 1) are… CONTINUE READING

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