hsa-mir-499 rs3746444 gene polymorphism is associated with susceptibility to breast cancer in an Iranian population.

@article{Omrani2014hsamir499RG,
  title={hsa-mir-499 rs3746444 gene polymorphism is associated with susceptibility to breast cancer in an Iranian population.},
  author={Mohsen Omrani and Mohammad Esmaeil Fazl Hashemi and Ebrahim Eskandari-Nasab and S E Hasani and Mohammad Ali Mashhadi and Farshid Arbabi and Mohsen Taheri},
  journal={Biomarkers in medicine},
  year={2014},
  volume={8 2},
  pages={259-67}
}
AIM Our study aimed to evaluate the possible association between four miRNA polymorphisms, hsa-miR-146a (rs2910164 G>C), hsa-miR-499 (rs3746444 T>C) and hsa-miRNA-196a2 (rs11614913 C>T and rs185070757 T>G), and susceptibility to breast cancer in an Iranian population. MATERIALS & METHODS In this case-control study we enrolled 236 patients with breast cancer and 203 healthy individuals. Tetra primer amplification refractory mutation system PCR was applied for genotyping the four miRNA SNPs… CONTINUE READING

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