hnRNP-R regulates the PMA-induced c-fos expression in retinal cells

@article{Huang2008hnRNPRRT,
  title={hnRNP-R regulates the PMA-induced c-fos expression in retinal cells},
  author={Jia Huang and Shu-jing Li and Xian-hua Chen and Yu Han and Ping Xu},
  journal={Cellular & Molecular Biology Letters},
  year={2008},
  volume={13},
  pages={303-311}
}
This study focused on the function of hnRNP-R in the regulation of c-fos expression. We demonstrated that hnRNP-R accelerated the rise and decline phases of c-fos mRNAs and Fos proteins, allowing PMA to induce an augmented pulse response of c-fos expression. Then, we examined the role of the c-fos-derived AU-rich element (ARE) in hnRNP-R-regulated mRNA degradation. Studies with the ARE-GFP reporter gene showed that hnRNP-R significantly reduced the expression of GFP with an inserted ARE… CONTINUE READING

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
9 Extracted Citations
21 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-9 of 9 extracted citations

Referenced Papers

Publications referenced by this paper.
Showing 1-10 of 21 references

a role for Smn in RNA processing in motor axons? Hum

  • W. Rossoll, A. K. Kroning, +7 authors gry-rbphnRNP-Q
  • Mol. Genet. 11
  • 2002
Highly Influential
3 Excerpts

a stressful (re)view from a functional map

  • Kovacs, K. J. c-fos as a transcription factor
  • Neurochem. Int. 33
  • 1998
Highly Influential
5 Excerpts

Similar Papers

Loading similar papers…