hem6: an ENU-induced recessive hypochromic microcytic anemia mutation in the mouse.

Abstract

Mouse models have proven invaluable for understanding erythropoiesis. Here, we describe an autosomal recessive, inherited anemia in the mouse mutant hem6. Hematologic and transplantation analyses reveal a mild, congenital, hypochromic, microcytic anemia intrinsic to the hematopoietic system that is associated with a decreased red blood cell zinc… (More)
DOI: 10.1182/blood-2007-09-111500

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