hedgehog is required for the proliferation and specification of ovarian somatic cells prior to egg chamber formation in Drosophila.

@article{Forbes1996hedgehogIR,
  title={hedgehog is required for the proliferation and specification of ovarian somatic cells prior to egg chamber formation in Drosophila.},
  author={Alexandria Forbes and Hai-yan Lin and Philip W Ingham and Allan C Spradling},
  journal={Development},
  year={1996},
  volume={122 4},
  pages={1125-35}
}
The hedgehog (hh) gene plays a role in regulating cell proliferation and specifying cell identity in diverse systems. We show that hh is expressed at the extreme apical end of Drosophila ovarioles in terminal filament cells and a newly identified group of associated somatic cells. Reducing or ectopically expressing hh affects somatic cells in region 2 of the germarium, 2-5 cells away from the cells in which Hh protein is detected. hh activity stimulates the proliferation of pre-follicle somatic… CONTINUE READING
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