hTERT extends proliferative lifespan and prevents oxidative stress-induced apoptosis in human lens epithelial cells.

Abstract

PURPOSE Telomerase is a specialized polymerase that catalyzes synthesis of telomeres in most eukaryotes. When introduced into somatic cells, it extends the proliferative lifespan and prevents replicative senescence. Whether it has similar functions in lens epithelial cells, especially in human lens epithelial cells (HLECs) remains to be determined. In this… (More)

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