hNOA1 interacts with complex I and DAP3 and regulates mitochondrial respiration and apoptosis.

@article{Tang2009hNOA1IW,
  title={hNOA1 interacts with complex I and DAP3 and regulates mitochondrial respiration and apoptosis.},
  author={Tingdong Tang and Bin Zheng and Sheng-hong Chen and Anne N Murphy and Krystyna Kudlicka and Huilin Zhou and Marilyn Gist Farquhar},
  journal={The Journal of biological chemistry},
  year={2009},
  volume={284 8},
  pages={
          5414-24
        }
}
Mitochondria are dynamic organelles that play key roles in metabolism, energy production, and apoptosis. Coordination of these processes is essential to maintain normal cellular functions. Here we characterized hNOA1, the human homologue of AtNOA1 (Arabidopsis thaliana nitric oxide-associated protein 1), a large mitochondrial GTPase. By immunofluorescence, immunoelectron microscopy, and mitochondrial subfractionation, endogenous hNOA1 is localized within mitochondria where it is peripherally… CONTINUE READING

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