hDbr1 is a nucleocytoplasmic shuttling protein with a protein phosphatase-like motif essential for debranching activity

@inproceedings{Kataoka2013hDbr1IA,
  title={hDbr1 is a nucleocytoplasmic shuttling protein with a protein phosphatase-like motif essential for debranching activity},
  author={Naoyuki Kataoka and Izumi Dobashi and Masatoshi Hagiwara and Mutsuhito Ohno},
  booktitle={Scientific reports},
  year={2013}
}
In higher eukaryotes most genes contain multiple introns. Introns are excised from pre-mRNAs by splicing and eventually degraded in the nucleus. It is likely that rapid intron turnover in the nucleus is important in higher eukaryotes, but this pathway is poorly understood. In order to gain insights into this pathway, we analyzed the human lariat RNA debranching enzyme1 (hDbr1) protein that catalyzes debranching of lariat-intron RNAs. Transfection experiments demonstrate that hDbr1 is localized… CONTINUE READING
Highly Cited
This paper has 461 citations. REVIEW CITATIONS
Recent Discussions
This paper has been referenced on Twitter 2 times over the past 90 days. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-8 of 8 extracted citations

462 Citations

010020030020142015201620172018
Citations per Year
Semantic Scholar estimates that this publication has 462 citations based on the available data.

See our FAQ for additional information.

References

Publications referenced by this paper.
Showing 1-10 of 58 references

Similar Papers

Loading similar papers…