gomelatine reverses the decrease in hippocampal cell survival induced by hronic mild stress

  • irstautė Dagytė, Ilaria Crescentea, +5 authors Jaap M. Koolhaasc
  • Published 2010
The antidepressant agomelatine is a MT1/MT2 receptor agonist and 5-HT2C antagonist. Its antidepressant activity is proposed to result from the synergy between these sets of receptors. Agomelatine-induced changes in the brain have been reported under basal conditions. Yet, little is known about its effects in the brain exposed to chronic stress as a risk… (More)