gammadelta T cells of human early pregnancy decidua: evidence for cytotoxic potency.

@article{MinchevaNilsson2000gammadeltaTC,
  title={gammadelta T cells of human early pregnancy decidua: evidence for cytotoxic potency.},
  author={Lucia Mincheva-Nilsson and Olga Nagaeva and Kerstin Sundqvist and M L Hammarstr{\"o}m and Sten G. Hammarstr{\"o}m and Vladimir Baranov},
  journal={International immunology},
  year={2000},
  volume={12 5},
  pages={585-96}
}
The immune compromise in decidua allows a semiallogeneic fetus to survive without impairing the ability of the maternal immune system to fight infections. Cytotoxic mechanisms are likely to be important in this compromise. Using RT-PCR, immunoflow cytometry and immunoelectron microscopy, the cytotoxic potential of isolated human decidual gammadelta T cells was studied. mRNA for perforin (Pf), granzymes A and B, granulysin and Fas ligand (FasL) was simultaneously expressed in decidual gammadelta… CONTINUE READING

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