gamma-Interferon production in peripheral blood mononuclear cells and tumor infiltrating lymphocytes from Kaposi's sarcoma patients: correlation with the presence of human herpesvirus-8 in peripheral blood mononuclear cells and lesional macrophages.

@article{Sirianni1998gammaInterferonPI,
  title={gamma-Interferon production in peripheral blood mononuclear cells and tumor infiltrating lymphocytes from Kaposi's sarcoma patients: correlation with the presence of human herpesvirus-8 in peripheral blood mononuclear cells and lesional macrophages.},
  author={Maria Caterina Sirianni and Laura Vincenzi and Valeria Fiorelli and Simone Topino and Enrico Scala and Stefania Uccini and A. Angeloni and Alberto Faggioni and Decio Cerimele and Francesca Cottoni and Fernando Aiuti and Barbara Ensoli},
  journal={Blood},
  year={1998},
  volume={91 3},
  pages={968-76}
}
Evidence indicates that, at least in the early stage, Kaposi's sarcoma (KS) is a cytokine-mediated disease and that it is consistently associated with a novel herpesvirus termed human herpesvirus-8 (HHV-8). To gain insights into the mechanisms by which cytokines and HHV-8 may cooperate in disease pathogenesis, we examined the phenotype, the Th1 (gamma-interferon [gamma IFN]) and Th2 (interleukin-4 [IL-4] cytokine profile and the presence of HHV-8 in peripheral blood mononuclear cells (PBMC… CONTINUE READING
38 Citations
85 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 38 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 85 references

Kaposi’s sarcoma-associated herpesvirus/ human herpesvirus 8 is not detectable in peripheral blood mononuclear cells of the relatives of sporadic KS patients

  • S Uccini, E Pilozzi, +10 authors F Cottoni
  • J Invest Dermatol 108:119,
  • 1997

Similar Papers

Loading similar papers…