feG-COOH blunts eosinophilic airway inflammation in a feline model of allergic asthma

@article{DeClue2009feGCOOHBE,
  title={feG-COOH blunts eosinophilic airway inflammation in a feline model of allergic asthma},
  author={A. DeClue and E. Schooley and Laura A. Nafe and C. Reinero},
  journal={Inflammation Research},
  year={2009},
  volume={58},
  pages={457-462}
}
Objective and designThis study investigated if feG-COOH would decrease allergen-induced airway inflammation.Materials or subjectsSeven adult cats sensitised to Bermuda grass allergen (BGA) to induce an asthmatic phenotype.TreatmentCats were randomized to receive either feG-COOH (1 mg/kg, PO) or placebo (saline 1 ml, PO) immediately prior to BGA aerosol challenge in a cross-over design.MethodsBronchoalveolar lavage fluid (BALF) was collected and airway inflammatory response assessed via… Expand
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