fMRI study of episodic memory in relapsing-remitting MS: correlation with T2 lesion volume.

@article{Bobholz2006fMRISO,
  title={fMRI study of episodic memory in relapsing-remitting MS: correlation with T2 lesion volume.},
  author={Julie A. Bobholz and Stephen M. Rao and L J Lobeck and Cathy Elsinger and Angela M Gleason and Jason E Kanz and Sally Durgerian and Edwin Maas},
  journal={Neurology},
  year={2006},
  volume={67 9},
  pages={1640-5}
}
OBJECTIVE To determine whether memory loss in patients with multiple sclerosis (MS) results from faulty encoding or retrieval, we correlated extent of T2-weighted lesion involvement with brain activation patterns on fMRI scans obtained while patients performed a verbal episodic memory task. METHODS We performed a neurologic examination, neuropsychological testing, and an event-related fMRI scan on 36 patients with relapsing-remitting MS. In addition, we obtained T2-weighted structural MRI… CONTINUE READING

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