fMRI of thermal pain: effects of stimulus laterality and attention.

@article{Brooks2002fMRIOT,
  title={fMRI of thermal pain: effects of stimulus laterality and attention.},
  author={Jonathan C. W. Brooks and T. Nurmikko and William E. Bimson and Krish D. Singh and Neil Roberts},
  journal={NeuroImage},
  year={2002},
  volume={15 2},
  pages={293-301}
}
Brain activity was studied by fMRI in 18 healthy subjects during stimulation of the thenar eminence of the hand with either warm (non-painful, 40 degrees C) or hot (painful, 46-49 degrees C) stimuli using a contact thermode. Experiments were performed on the right and left hand independently and with two attentional contexts: subjects either attended to pain or attended to a visual global motion discrimination task (to distract them from pain). Group analysis demonstrated that attended warm… CONTINUE READING
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Painful thermal stimulation of either hand elicited significant activity over a large network of brain regions , including insula , inferior frontal gyrus , cingulate gyrus , secondary somatosensory cortex , cerebellum , and medial frontal gyrus ( corrected P < 0.05 ) .
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