fMRI of generalized absence status epilepticus in conscious marmoset monkeys reveals corticothalamic activation.

@article{Tenney2004fMRIOG,
  title={fMRI of generalized absence status epilepticus in conscious marmoset monkeys reveals corticothalamic activation.},
  author={Jeffrey R. Tenney and Paul C Marshall and Jean A. King and Craig F Ferris},
  journal={Epilepsia},
  year={2004},
  volume={45 10},
  pages={1240-7}
}
PURPOSE A nonhuman primate model of generalized absence status epilepticus was developed for use in functional magnetic resonance imaging (fMRI) experiments to elucidate the brain mechanisms underlying this disorder. METHODS Adult male marmoset monkeys (Callithrix jacchus) were treated with gamma-butyrolactone (GBL) to induce prolonged absence seizures, and the resulting spike-wave discharges (SWDs) were analyzed to determine the similarity to the 3-Hz SWDs that characterize the disorder. In… CONTINUE READING

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