f-Adrenergic receptors in rat liver : Effects of adrenalectomy ( iodohydroxybenzylpindolol binding / supersensitivity of adenylate cyclase / hormone receptors in liver )

The response of rat liver adenylate cyclase [ATP pyrophosphate-lyase (cyclizing), EC] to catecholamines is enhanced after adrenalectomy. To investigate this phenomenon, we developed an in vitro assay for #-adrenergic receptors of plasma membranes derived from livers of control and adrenalectomized rats, using [l25I~iodohydroxybenzylpindolol (IHYP… CONTINUE READING