• Corpus ID: 40681940

eview revention of tick-borne encephalitis by FSME-IMMUN ® vaccines : Review of a linical development programme lexandra

  title={eview revention of tick-borne encephalitis by FSME-IMMUN {\textregistered} vaccines : Review of a linical development programme lexandra},
  author={Loew-Baselli and E Poellabauer and Borislava G. Pavlova and Sandor Fritsch and Clair L. Firth and obert Petermann and P. Noel Barrett and Hartmut Josef Ehrlich},
The need for highly effective tick-borne encephalitis (TBE) vaccines has increased globally due to a variety of factors including climate, social, economic and demographic changes, which are thought to have promoted the expansion of the endemic region of TBE viruses. The first TBE vaccine, FSME-IMMUN® Inject, was introduced in the 1970s and has been continually improved since then to enhance both its safety and immunogenicity. The current formulation was established in 2001 and is marketed as… 

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Field effectiveness of vaccination against tick-borne encephalitis.
Stimulation of the immune system by different TBE-virus vaccines.
Seropersistence of tick-borne encephalitis antibodies, safety and booster response to FSME-IMMUN® 0.5 ml in adults aged 18-67 years
A booster vaccination with FSME-IMMUN®, administered 3 years after primary vaccination, is well tolerated and induces a substantial immune response regardless of vaccine used in the primary series.
Serological response to tick-borne encephalitis (TBE) vaccination in the elderly – results from an observational study
After two doses of TBE vaccine, one in five persons aged 60 years or older may be without protective antibodies, confirming the importance of testing the antibody response after the second vaccination and administering an additional dose in the event of insufficient response.
Tick-borne encephalitis and the impact of vaccination.
Austria is the country with the highest coverage of TBE vaccination and this has led to a dramatic reduction in the annual number of clinical cases and proves under field conditions that vaccination is an effective means for the prophylaxis of T BE.