edgeRun: an R package for sensitive, functionally relevant differential expression discovery using an unconditional exact test

@inproceedings{Dimont2015edgeRunAR,
  title={edgeRun: an R package for sensitive, functionally relevant differential expression discovery using an unconditional exact test},
  author={Emmanuel Dimont and Jiantao Shi and Rory Kirchner and Winston A Hide},
  booktitle={Bioinformatics},
  year={2015}
}
Next-generation sequencing platforms for measuring digital expression such as RNA-Seq are displacing traditional microarray-based methods in biological experiments. The detection of differentially expressed genes between groups of biological conditions has led to the development of numerous bioinformatics tools, but so far, few exploit the expanded dynamic range afforded by the new technologies. We present edgeRun, an R package that implements an unconditional exact test that is a more powerful… CONTINUE READING
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Statistical Methods for Research Workers

  • R. A. Fisher
  • Oliver and Boyd, Edinburgh
  • 1925
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