eNOS expression is not altered in pulmonary vascular remodeling due to increased pulmonary blood flow.

@article{Everett1998eNOSEI,
  title={eNOS expression is not altered in pulmonary vascular remodeling due to increased pulmonary blood flow.},
  author={Allen Dale Everett and Timothy D Le Cras and Chun Yi Xue and Roger A. Johns},
  journal={The American journal of physiology},
  year={1998},
  volume={274 6 Pt 1},
  pages={L1058-65}
}
Congenital heart lesions resulting in increased pulmonary blood flow are common and if unrepaired often lead to pulmonary hypertension and heart failure. Therefore, we hypothesized that increased pulmonary blood flow without changes in pressure would result in remodeling of the pulmonary arterial wall. Furthermore, because the vasodilator nitric oxide is produced by the lung, is regulated by flow in the systemic circulation, and has been associated with the regulation of smooth muscle cell… CONTINUE READING