eNOS and BDKRB2 genotypes affect the antihypertensive responses to enalapril

@article{Silva2012eNOSAB,
  title={eNOS and BDKRB2 genotypes affect the antihypertensive responses to enalapril},
  author={P. S. Silva and Vanessa Fontana and Marcelo Rizzatti Luizon and Riccardo Lacchini and Welder A. Silva and Celso Biagi and Jos{\'e} Eduardo Tanus-Santos},
  journal={European Journal of Clinical Pharmacology},
  year={2012},
  volume={69},
  pages={167-177}
}
PurposeThe antihypertensive effect of angiotensin-converting enzyme inhibitors (ACEi) is attributed partially to increased nitric oxide bioavailability. It is possible that functional polymorphisms in endothelial nitric oxide synthase (eNOS) and bradykinin receptor B2 (BDKRB2) genes may affect the antihypertensive response to enalapril.MethodsWe evaluated 106 hypertensive patients treated only with enalapril for 60 days. The difference between the mean arterial pressure (MAP) before and after… 

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TLDR
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