eCVAM coordinated a formal prevalidation study of the SHe


As part of the human safety assessment of new chemical compounds, carcinogenicity testing currently is based on the standard 2-year rodent assay (OeCD, 2008). However, this assay is time-consuming, costly, and requires a large number of animals. the in vitro Cell transformation Assay (CtA) has been proposed as a valuable alternative to the bioassay. the CtA… (More)


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