dnm1 deletion blocks mitochondrial fragmentation in Δfzo1 cells

@article{Yang2020dnm1DB,
  title={dnm1 deletion blocks mitochondrial fragmentation in $\Delta$fzo1 cells},
  author={Yanmei Yang and Yinzhi Hu and Lin Wu and Pan Zhang and Jinjie Shang},
  journal={Yeast},
  year={2020},
  volume={38},
  pages={197 - 205}
}
Mitochondrial division and fusion play critical roles in maintaining functional mitochondria. Fzo1 is an outer mitochondrial membrane GTPase that played an essential role in mitochondrial fusion in budding yeast Saccharomyces cerevisiae. Here, we report the characterization of the Schizosaccharomyces pombe homologue of S. cerevisiae Fzo1p, Fzo1. Disruption of the fzo1 gene in S. pombe results in a fragmented mitochondrial morphology and a dramatically reduced growth on glycerol medium phenotype… 
3 Citations
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