dishevelled and armadillo act in the Wingless signalling pathway in Drosophila

@article{Noordermeer1994dishevelledAA,
  title={dishevelled and armadillo act in the Wingless signalling pathway in Drosophila},
  author={Jasprien Noordermeer and John Klingensmith and Norbert Perrimon and Roeland Nusse},
  journal={Nature},
  year={1994},
  volume={367},
  pages={80-83}
}
THE Wnt genes encode conserved secreted proteins that play a role in normal development and tumorigenesis1,2. Little is known about the signal transduction pathways of Wnt gene products. One of the best characterized Wnt family members is the Drosophila segment polarity gene wingless 3–6. We have investigated whether segment polarity genes with a wingless-like phenotype mediate the wingless signal. We used a wingless transgene controlled by a heat-shock promoter for genetic epistasis… CONTINUE READING
Highly Influential
This paper has highly influenced 10 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

From This Paper

Topics from this paper.
137 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 137 extracted citations

Similar Papers

Loading similar papers…